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1.What is the AMENTOFLAVONE ?

Amentoflavone is a biflavonoid originally isolated from Selaginella. It has a wide variety of biological effects including antibacterial, antioxidant, antiviral, antidiabetic, and neuroprotective activities. Amentoflavone has antiviral activity against the influenza A subtypes H1N1 and H3N2, influenza B, and herpes simplex virus 1 (EC50s = 3.1 and 4.3, 0.56, and 17.9 μg/ml, respectively). It has antidiabetic effects such that it dose-dependently increases insulin receptor phosphorylation and activation and inhibits hydrolysis of p-nitrophenyl phosphate (p-NPP) catalyzed by protein tyrosine phosphatase 1B (PTP1B; IC50 = 7.3 μM). Amentoflavone reduces the time mice spend immobile in the forced swim test, a measure of antidepressant efficacy, in a dose-dependent manner.

2.What is the CAS number for AMENTOFLAVONE ?

The CAS number of AMENTOFLAVONE is 1617-53-4.

3.What are another words for AMENTOFLAVONE ?

Synonyms?for?AMENTOFLAVONE 1617-53-4:3''',8-Biflavone,4',4''',5,5'',7,7''-hexahydroxy- (7CI,8CI);Ginkgetin, didemethyl- (6CI);Amenthoflavone;I3',II8-Biapigenin;NSC 295677;Tridemethylsciadopitysin;

4.What is AMENTOFLAVONE (1617-53-4) used for?

Amentoflavone, is isolated from an Et acetate ext. of the whole plant of Selaginella tamariscina. It has been shown to have antitumor activity, such as mitochondria-mediated apoptotic cell death. Amentoflavone can interact with many medications by being a potent inhibitor of CYP3A4 and CYP2C9, which are enzymes responsible for the metabolism of some drugs in the body.

InChI:InChI=1/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12,31-36H

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