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Good factory supply good Choline hydroxide 123-41-1
- Molecular Formula: C5H15NO2
- Molecular Weight: 121.18
- Appearance/Colour: clear light yellow viscous solution
- Vapor Pressure: 28.284hPa at 25℃
- Melting Point: 236～239℃
- Refractive Index: n20/D 1.4304
- PKA: 13.9(at 25℃)
- Flash Point: 92°F
- PSA： 43.29000
- Density: 1.09 g/mL at 20 °C
- LogP: -0.49190
Choline hydroxide(Cas 123-41-1) Usage
|
Definition |
An amino alcohol,CH2OHCH2N(CH3)3OH. It occurswidely in living organisms as aconstituent of certain types ofphospholipids– the lecithins andsphingomyelins– and in the neurotransmitteracetylcholine. It issometimes classified as a memberof the vitamin B complex. |
|
Flammability and Explosibility |
Nonflammable |
InChI:InChI=1/C5H14NO/c1-6(2,3)4-5-7/h7H,4-5H2,1-3H3/q+1
123-41-1 Relevant articles
Alendronic acid as ionic liquid: New perspective on osteosarcoma
Branco, Luís C.,Costa-Rodrigues, Jo?o,Fernandes, Maria H.,Santos, Miguel M.,Teixeira, Sónia
, (2020)
Herein the quantitative synthesis of eig...
Highly efficient green synthesis of the photochromic spironaphthoxazines using an eco-friendly choline hydroxide catalyst
Vajekar, Shailesh N.,Shankarling, Ganapati S.
, p. 338 - 347 (2020)
A greener route for the synthesis of the...
Synthesis and thermophysical properties of biocompatible cholinium-based amino acid ionic liquids
Tao, Duan-Jian,Cheng, Zheng,Chen, Feng-Feng,Li, Zhang-Min,Hu, Na,Chen, Xiang-Shu
, p. 1542 - 1548 (2013)
Nowadays the knowledge of thermodynamic ...
Functional ionic liquid from biorenewable materials: synthesis and application as a catalyst in direct aldol reactions
Hu, Suqin,Jiang, Tao,Zhang, Zhaofu,Zhu, Anlian,Han, Buxing,Song, Jinliang,Xie, Ye,Li, Wenjing
, p. 5613 - 5617 (2007)
A new room temperature ionic liquid (IL)...
Biofriendly ionic liquids for starch plasticization: A screening approach
Colomines,Decaen,Lourdin,Leroy
, p. 90331 - 90337 (2016)
A series of cholinium cation-based bioio...
-
Bremer,Greenberg
, (1960)
-
Environmentally benign synthesis of 4-aminoquinoline-2-ones using recyclable choline hydroxide
Sanap, Anita Kailas,Shankarling, Ganapati Subray
, p. 206 - 212 (2015)
Greener synthesis of 4-aminoquinoline-2-...
The "neutral" hydrolysis of simple carboxylic esters in water and the rate enhancements produced by acetylcholinesterase and other carboxylic acid esterases
Wolfenden, Richard,Yuan, Yang
, p. 13821 - 13823 (2011)
Experiments at elevated temperatures per...
Greener route for the synthesis of photo- and thermochromic spiropyrans using a highly efficient, reusable, and biocompatible choline hydroxide in an aqueous medium
Pargaonkar, Jyotsna G.,Patil, Sanjay K.,Vajekar, Shailesh N.
, p. 208 - 215 (2018)
Here, we report the synthesis of photo- ...
Shape-selective production of zinc phosphate in aqueous and nonaqueous media using (2-hydroxyethyl) trimethylammonium hydroxide-assisted sonochemical route
Samadi-Maybodi, Abdolraouf,Nejad-Darzi, Seyed Karim Hassani
, p. 431 - 439 (2012)
Zinc phosphatemolecular sieveswere synth...
Bifunctional Ionic Liquids Derived from Biorenewable Sources as Sustainable Catalysts for Fixation of Carbon Dioxide
Saptal, Vitthal B.,Bhanage, Bhalchandra M.
, p. 1145 - 1151 (2017)
A series of highly efficient, bifunction...
Synthesis of phosphorous acid and its derivatives based on the reaction of elemental phosphorus (P4) and aqueous solution of choline in the presence of the hydroxides of earth alkali metals
Platova, Elena V.,Batyeva, Elvira S.,Kursheva, Lidiya I.,Sinyashin, Oleg G.
, p. 517 - 519 (2008)
A nonchloric method for the synthesis of...
Synthesis of hydrotalcites from waste steel slag with [Bmim]OH intercalated for the transesterification of glycerol carbonate
Liu, Guanhao,Xu, Xinru,Yang, Jingyi
, (2020)
Ca-Mg-Al hydrotalcites were prepared by ...
Elucidation of the effect of some cholinium amino acid ionic liquids on the thermal and the conformational stability of insulin
Guncheva,Ossowicz,Janus,Todinova,Yancheva
, p. 257 - 262 (2019)
The major concerns about protein-based d...
Design of environmentally friendly ionic liquid aqueous two-phase systems for the efficient and high activity extraction of proteins
Li, Zhiyong,Liu, Xinxin,Pei, Yuanchao,Wang, Jianji,He, Mingyuan
, p. 2941 - 2950,10 (2012)
Ionic liquids (ILs) have numerous applic...
Antimicrobial activities of highly bioavailable organic salts and ionic liquids from fluoroquinolones
Alves, Celso,Branco, Luís C.,Costa, Alexandra,Florindo, Catarina,Marrucho, Isabel M.,Pedrosa, Rui,Petrovski, ?eljko,Santos, Miguel M.,Silva, Joana
, p. 1 - 15 (2020)
As the development of novel antibiotics ...
Deep eutectic solvent: A simple, environmentally benign reaction media for regioselective synthesis of 2,3,4-trisubstituted 1H-pyrroles
Kalmode, Hanuman P.,Vadagaonkar, Kamlesh S.,Murugan, Kaliyappan,Prakash, Sattey,Chaskar, Atul C.
, p. 35166 - 35174 (2015)
Choline hydroxide has been successfully ...
Greener [3+3] tandem annulation-oxidation approach towards the synthesis of substituted pyrimidines
Vadagaonkar, Kamlesh S.,Kalmode, Hanuman P.,Prakash, Sattey,Chaskar, Atul C.
, p. 3639 - 3645 (2015)
An economical and green synthesis of par...
Enantioselective liquid-liquid extraction of valine enantiomers in the aqueous two-phase system formed by the cholinium amino acid ionic liquid copper complexes and salt
Liu, Lianglei,Sun, Danyu,Li, Fenfang,Ma, Shaoping,Tan, Zhijian
, (2019)
It was widely reported that the heterocy...
Choline and amino acid based biocompatible ionic liquid mediated transdermal delivery of the sparingly soluble drug acyclovir
Chowdhury, Md. Raihan,Goto, Masahiro,Islam, Md. Rafiqul,Kamiya, Noriho,Moniruzzaman, Muhammad,Tahara, Yoshiro,Wakabayashi, Rie
, (2020)
Transdermal delivery of drugs is more ch...
An efficient and reusable ionic liquid catalyst for the synthesis of 14-aryl-14H-dibenzo[a,j]xanthenes under solvent-free conditions
Zhu, Anlian,Bai, Shukun,Jin, Wei,Liu, Ruixia,Li, Lingjun,Zhao, Yang,Wang, Jianji
, p. 36031 - 36035 (2014)
In this work, it was found that acidic p...
-
Bremer,Figard,Greenberg
, p. 477 (1960)
-
Highly efficient green synthesis of α-hydroxyphosphonates using a recyclable choline hydroxide catalyst
Kalla, Reddi Mohan Naidu,Zhang, Yu,Kim, Il
, p. 5373 - 5379 (2017)
Choline hydroxide has been found to be a...
Favipiravir-Based Ionic Liquids as Potent Antiviral Drugs for Oral Delivery: Synthesis, Solubility, and Pharmacokinetic Evaluation
Moshikur, Rahman Md,Ali, Md. Korban,Wakabayashi, Rie,Moniruzzaman, Muhammad,Goto, Masahiro
, p. 3108 - 3115 (2021)
Coronavirus disease 2019 (COVID-19) has ...
Ionic Liquids and Salts from Ibuprofen as Promising Innovative Formulations of an Old Drug
Santos, Miguel M.,Raposo, Luís R.,Carrera, Gon?alo V. S. M.,Costa, Alexandra,Dionísio, Madalena,Baptista, Pedro V.,Fernandes, Alexandra R.,Branco, Luís C.
, p. 907 - 911 (2019)
Herein we report the synthesis of novel ...
-
Le Heux
, p. 570 (1924)
-
Preparation and characterization of new ionic liquid forms of 2,4-DP herbicide
Niemczak, Micha?,Biedziak, Agnieszka,Czerniak, Kamil,Marcinkowska, Katarzyna
, p. 7315 - 7325 (2017)
In this study, a series of new 2-(2,4-di...
Nano-magnetic-iron Oxides@choline Acetate as a Heterogeneous Catalyst for the Synthesis of 1,2,3-Triazoles
Heydari, Akbar,Mohammadkhani, Abolfazl
, (2021/08/09)
In this research, four cholines supporte...
Choline hydroxide promoted sustainable one-pot three-component synthesis of 1H-pyrazolo[1,2-a]pyridazine-2-carbonitriles under solvent-free conditions
Vajekar, Shailesh N.,Shankarling, Ganapati S.
supporting information, p. 1147 - 1158 (2020/03/30)
A sustainable one-pot three-component sy...
123-41-1 Process route
-
-
67-48-1
choline chloride
-
-
123-41-1
cholin hydroxide
| Conditions | Yield |
|---|---|
|
With
silver(l) oxide;
|
|
|
With
717 anion-exchange resin;
In
water;
at 20 ℃;
pH=9;
|
|
|
With
anion exchange resin;
|
|
|
With
Amberlite resin CG-400 OH(1-)-form;
In
water;
|
|
|
With
Ambersep 900 OH;
|
|
|
With
water; silver(l) oxide;
|
|
|
With
anion exchange resin;
|
|
|
With
potassium hydroxide;
at 61 ℃;
for 12h;
|
|
|
With
potassium hydroxide;
In
methanol;
at 60 ℃;
for 12h;
|
|
|
With
potassium hydroxide;
In
methanol;
at 61 ℃;
for 12h;
|
|
|
With
hydroxide anion exchange resin;
|
|
|
With
potassium hydroxide;
In
ethanol;
at -25 ℃;
for 24h;
|
|
|
With
potassium hydroxide;
In
methanol;
for 12h;
Reflux;
Inert atmosphere;
|
|
|
With
water;
|
|
|
With
potassium hydroxide;
In
ethanol;
at 20 ℃;
for 1h;
|
|
|
With
potassium hydroxide;
In
methanol;
Reflux;
|
|
|
With
potassium hydroxide;
In
methanol;
for 8h;
Inert atmosphere;
Reflux;
|
|
|
With
potassium hydroxide;
In
methanol;
at 20 ℃;
for 12h;
Reflux;
|
|
|
With
potassium hydroxide;
In
methanol;
for 0.5h;
|
|
|
With
potassium hydroxide;
In
methanol;
at 60 ℃;
for 12h;
|
|
|
With
potassium hydroxide;
In
methanol;
Reflux;
|
|
|
With
ion-exchange column Amberlyst A26(OH);
In
methanol;
|
|
|
With
dowex Monosphere 550 A UPW (OH form) resin;
|
|
|
With
potassium hydroxide;
In
methanol;
at 20 ℃;
for 12h;
|
|
|
With
potassium hydroxide;
In
methanol;
at 600 ℃;
for 12h;
|
|
|
With
potassium hydroxide;
In
methanol;
at 60 ℃;
for 12h;
|
|
|
With
Amberlite IRA-400-OH ion-exchange column;
In
methanol;
|
|
|
With
water; silver(l) oxide;
at 20 ℃;
for 2h;
Darkness;
|
|
|
With
sodium hydroxide;
In
propan-1-ol;
at 70 - 72 ℃;
Inert atmosphere;
|
|
|
With
sodium hydroxide;
In
water;
|
|
|
With
Amberlyst IRA-400 (OH);
|
|
|
With
sodium hydroxide;
In
dichloromethane;
|
|
|
With
silver(l) oxide;
In
methanol;
|
|
|
With
sodium hydroxide;
In
methanol;
for 12h;
Reflux;
|
-
-
75-21-8,99932-75-9
oxirane
-
-
75-50-3
trimethylamine
-
-
123-41-1
cholin hydroxide
| Conditions | Yield |
|---|---|
|
With
water;
destilliert das ueberschuessige Trimethylamin ab und dampft im Hochvakuum ueber Phosphorpentoxyd ein;
|
|
|
With
water;
at 15 - 45 ℃;
under 1500.15 - 2250.23 Torr;
|
|
|
With
P4; H2O; Ba(OH)2;
at 50 - 100 ℃;
|
|
|
With
water;
at 35 - 40 ℃;
Concentration;
Temperature;
Time;
|
|
|
|
123-41-1 Upstream products
-
75-21-8
oxirane
-
75-50-3
trimethylamine
-
108-01-0
2-(N,N-dimethylamino)ethanol
-
462-10-2
DL-homocystine
123-41-1 Downstream products
-
60-27-5
creatinine
-
57-00-1
Creatinine
-
107-21-1
ethylene glycol
-
75-50-3
trimethylamine
