3-HYDROXY-2-METHYL-CYCLOPENT-2-ENONE

  • CAS No.: 5870-63-3
  • Purity: 99%
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Reputable factory supply 3-HYDROXY-2-METHYL-CYCLOPENT-2-ENONE 5870-63-3 in stock with high standard

  • Molecular Formula: C6H8 O2
  • Molecular Weight: 112.128
  • Melting Point: 213-215 °C(Solv: ethanol (64-17-5)) 
  • Boiling Point: 212.2°Cat760mmHg 
  • PKA: 4.82±0.30(Predicted) 
  • Flash Point: 84.4°C 
  • PSA: 37.30000 
  • Density: 1.225g/cm3 
  • LogP: 1.18130 

5870-63-3 Relevant articles

Conversion of cycloalk-2-enones into 2-methylcycloalkane-1,3-diones - Assessment of various Tamao-Fleming procedures and mechanistic insight into the use of the Me3SiMe2Si unit

Yu, Guojun,Clive, Derrick L. J.

, p. 1653 - 1664 (2016/02/10)

Conjugate addition of Me3SiMe2SiLi to cy...

Reactions of 1,2-bis(trimethylsilyloxy)cycloalkenes with the diethyl acetals of aldehydes

Gao, Fuye,Burnell, D. Jean

, p. 356 - 359 (2007/10/03)

Lewis acid-mediated reactions of 1,2-bis...

5870-63-3 Process route

2-methylcyclopentane-1,3-dione ethylene glycol monoacetal
54972-03-1

2-methylcyclopentane-1,3-dione ethylene glycol monoacetal

3-hydroxy-2-methyl-2-cyclopenten-1-one
5870-63-3

3-hydroxy-2-methyl-2-cyclopenten-1-one

Conditions
Conditions Yield
With hydrogenchloride; In tetrahydrofuran; water; for 10h;
71%
cyclopent-2-enone
930-30-3

cyclopent-2-enone

3-hydroxy-2-methyl-2-cyclopenten-1-one
5870-63-3

3-hydroxy-2-methyl-2-cyclopenten-1-one

Conditions
Conditions Yield
Multi-step reaction with 5 steps
1.1: N,N,N,N,N,N-hexamethylphosphoric triamide; methyllithium / diethyl ether / 0.5 h / 0 °C / Inert atmosphere
1.2: 1 h / -78 °C / Inert atmosphere
1.3: 3 h / -78 - 20 °C / Inert atmosphere
2.1: toluene-4-sulfonic acid / benzene / 6 h / Reflux; Dean-Stark
3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.33 h / Inert atmosphere
3.2: 20 h
4.1: tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide / dichloromethane / 0.5 h / Molecular sieve; Inert atmosphere
5.1: hydrogenchloride / tetrahydrofuran; water / 10 h
With hydrogenchloride; N,N,N,N,N,N-hexamethylphosphoric triamide; tetrapropylammonium perruthennate; tetrabutyl ammonium fluoride; methyllithium; toluene-4-sulfonic acid; 4-methylmorpholine N-oxide; In tetrahydrofuran; diethyl ether; dichloromethane; water; benzene; 3.2: |Tamao-Kumada Oxidation;

5870-63-3 Upstream products

  • 930-30-3
    930-30-3

    cyclopent-2-enone

  • 54972-03-1
    54972-03-1

    2-methylcyclopentane-1,3-dione ethylene glycol monoacetal

5870-63-3 Downstream products

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    3-methoxy-2-methylcyclopent-2-enone

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    2-Methylcyclopent-1,3-dione monoethyl enol ether

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