17alpha-Acetoxy-11beta-[4-(dimethylamino)phenyl]-21-methoxy-19-norpregna-4,9-diene- 3,20-dione
- CAS No.: 198414-31-2
- Purity: 99%
Top Quality 17alpha-Acetoxy-11beta-[4-(dimethylamino)phenyl]-21-methoxy-19-norpregna-4,9-diene- 3,20-dione 198414-31-2 Hot Sell In Stock
- Molecular Formula: C31H39NO5
- Molecular Weight: 505.654
198414-31-2 Relevant articles
Acetic acid etra si Tong and intermediate preparation method and use thereof
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Paragraph 0052-0053, (2017/07/13)
The invention relates to an intermediate...
PROCESS FOR THE PRODUCTION OF 21 -METHOXY-11 -BETA-PHENYL-19-NOR-PREGNA-4,9-DIENE-3,20-DIONE DERIVATIVES
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Page/Page column 15-16, (2015/09/22)
The present invention relates to a proce...
INDUSTRIAL METHOD FOR THE SYNTHESIS OF 17-ACETOXY-11beta-[4-(DIMETHYLAMINO)-PHENYL]-21-METHOXY-19-NORPREGNA-4,9-DIEN-3,20-DIONE AND THE KEY INTERMEDIATES OF THE PROCESS
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Page/Page column 12, (2010/06/16)
The present invention relates to a proce...
Structural modification of 19-norprogesterone I: 17-α-substituted-11-β-substituted-4-aryl and 21-substituted 19-norpregnadienedione as new antiprogestational agents
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, (2008/06/13)
The present invention relates, inter ali...
198414-31-2 Process route
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198414-30-1
Telapristone
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108-24-7
acetic anhydride
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-
198414-31-2
Telapristone acetate
| Conditions | Yield |
|---|---|
|
Telapristone; acetic anhydride;
With
perchloric acid;
In
dichloromethane;
at -25 - -15 ℃;
Industry scale;
With
ammonium hydroxide;
In
dichloromethane; water;
at 25 ℃;
pH=7 - 8;
Product distribution / selectivity;
Industry scale;
|
93.79%
|
|
With
perchloric acid;
In
dichloromethane;
at -25 - -15 ℃;
for 0.5h;
|
64%
|
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17α-hydroxy-21-methoxy-11β-[4-(N, N-dimethylamino)phenyl]-19-norpregn-4, 9(10)-diene-3,20-dione
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-
64-19-7,77671-22-8
acetic acid
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-
198414-31-2
Telapristone acetate
| Conditions | Yield |
|---|---|
|
With
toluene-4-sulfonic acid; trifluoroacetic anhydride;
In
dichloromethane;
at 20 ℃;
Cooling with ice;
|
0.5 g
|
198414-31-2 Upstream products
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198414-30-1
Telapristone
-
108-24-7
acetic anhydride
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91934-94-0
11β-[4-(N,N-dimethylamino)phenyl]-3,3-ethylenedioxy-5α-hydroxy-17α-[(trimethylsilyl)oxy]-5α-estr-9-en-17β-carbonitrile
-
1094602-02-4
11β-[4-(N,N-dimethylamino)phenyl]-3,3-ethylenedioxy-5,17α-bis[(trimethylsilyl)oxy]-5α-estr-9-en-17β-carbonitrile
198414-31-2 Downstream products
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777861-40-2
17α-acetoxy-21-methoxy-11β-(4-N,N-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione hydrobromide
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1040179-92-7
17α-acetoxy-11β-[4-(N,N-dimethylamino)phenyl]-21-methoxy-19-norpregna-4,9(10)-diene-3,20-dione methanesulfonate
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1040179-90-5
17α-acetoxy-11β-[4-(N,N-dimethylamino)phenyl]-21-methoxy-19-norpregna-4,9(10)-diene-3,20-dione perchlorate