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Quality products?make an important contribution to long-term revenue and profitability. Buy high quality and low price 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one 55314-16-4 now
1.What is the 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one ?
3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one is used ads pharmaceutical intermediate, an imatinib intermediate.
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350-03-8
methyl-3-pyridylketone
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4637-24-5
N ,N -dimethyl-formamide dimethyl acetal
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55314-16-4,75415-01-9,123367-26-0
3-(N,N-dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one
| Conditions | Yield |
|---|---|
|
In
neat (no solvent);
at 65 - 100 ℃;
|
96%
|
|
at 85 ℃;
for 10h;
Large scale;
|
95%
|
|
In
5,5-dimethyl-1,3-cyclohexadiene;
for 20h;
Reflux;
|
94%
|
|
In
para-xylene;
Reflux;
|
94%
|
|
at 100 ℃;
for 16h;
Inert atmosphere;
|
92.6%
|
|
With
acetic acid;
at 90 - 95 ℃;
for 2h;
Product distribution / selectivity;
|
92%
|
|
In
5,5-dimethyl-1,3-cyclohexadiene;
at 140 ℃;
for 20h;
Inert atmosphere;
Schlenk technique;
|
92.6%
|
|
In
5,5-dimethyl-1,3-cyclohexadiene;
at 140 ℃;
|
92%
|
|
In
5,5-dimethyl-1,3-cyclohexadiene;
at 140 ℃;
for 20h;
|
90%
|
|
In
o-xylene;
at 130 ℃;
for 20h;
|
90%
|
|
In
5,5-dimethyl-1,3-cyclohexadiene;
Reflux;
|
87%
|
|
Reflux;
|
85%
|
|
In
neat (no solvent);
for 23h;
Reflux;
|
85%
|
|
In
5,5-dimethyl-1,3-cyclohexadiene;
for 21h;
Reflux;
|
83.3%
|
|
for 4h;
Reflux;
Neat (no solvent);
|
82%
|
|
Reflux;
|
82%
|
|
In
ethanol;
at 20 ℃;
for 12h;
Reflux;
|
72%
|
|
In
ethanol;
for 12h;
Reflux;
|
70%
|
|
In
ethanol;
for 12h;
Inert atmosphere;
Reflux;
|
70%
|
|
In
methanol;
for 10h;
Reflux;
|
60%
|
|
In
ethanol;
at 80 ℃;
for 16 - 18h;
Heating / reflux;
|
50.8%
|
|
In
ethanol;
Heating;
|
|
|
methyl-3-pyridylketone; N,N-dimethyl-formamide dimethyl acetal;
for 23h;
Heating / reflux;
at 0 ℃;
|
|
|
In
ethanol;
Reflux;
Inert atmosphere;
|
|
|
In
toluene;
for 24h;
Reflux;
|
|
|
Reflux;
|
|
|
for 6h;
Reflux;
|
|
|
In
toluene;
for 18h;
Inert atmosphere;
Reflux;
|
|
|
Reflux;
|
|
|
at 100 ℃;
for 12h;
Inert atmosphere;
neat (no solvent);
|
|
|
at 25 - 80 ℃;
for 2h;
Inert atmosphere;
|
60.2 g
|
|
In
5,5-dimethyl-1,3-cyclohexadiene;
for 24h;
Reflux;
|
|
|
at 170 ℃;
for 0.05h;
Sealed tube;
|
|
|
In
5,5-dimethyl-1,3-cyclohexadiene;
for 48h;
Reflux;
|
|
|
In
5,5-dimethyl-1,3-cyclohexadiene;
Reflux;
|
|
|
In
toluene;
at 120 ℃;
for 0.25h;
Microwave irradiation;
|
|
|
at 110 ℃;
|
|
|
for 16h;
Heating / reflux;
|
|
|
for 16h;
Heating / reflux;
|
|
|
for 16h;
Heating / reflux;
|
|
|
for 24h;
Reflux;
|
6.9 g
|
|
at 82 - 84 ℃;
for 8h;
|
|
|
at 103 ℃;
|
-
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350-03-8
methyl-3-pyridylketone
-
-
109-94-4
formic acid ethyl ester
-
-
55314-16-4,75415-01-9,123367-26-0
3-(N,N-dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one
| Conditions | Yield |
|---|---|
|
With
sodium; acetic acid; dimethyl amine;
In
methanol; hexane; toluene;
|
2.What is the CAS number for 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one ?
The CAS number of 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one is 55314-16-4.
More information of 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one 55314-16-4 are:
|
CAS?Number |
55314-16-4 |
|
Density |
1.071 g/cm3 |
|
Melting Point |
86-88 °C |
|
Boiling Point |
281.442 °C at 760 mmHg |
|
Flash Point |
124.012 °C |
|
Vapor Pressure |
0.00356mmHg at 25°C |
|
Refractive Index |
1.545 |
|
HS CODE |
29333990 |
|
PSA |
33.20000 |
|
LogP |
1.33960 |
|
Pka |
6.19±0.70(Predicted) |
3.What are another words for 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one ?
Synonyms?for?1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one 55314-16-4:3-(Dimethylamino)-1-(3-pyridinyl)-2-propen-1-one;3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one;3-Dimethylamino-1-(pyridin-3-yl)propenone;
4.What is the molecular formula of 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one?
The chemical formula of ?1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one is?C10 H12 N2 O which containing 10 Carbon atoms,12 Hydrogen atoms,2 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight of??1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one?is 176.218.
5.What is 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one (55314-16-4) used for?
1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one, also known as 3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one, is an off-white solid that serves as a crucial intermediate in the pharmaceutical industry. It is primarily recognized for its role in the synthesis of various drugs, including Rasagiline and Imatinib.
InChI:InChI=1/C10H12N2O/c1-12(2)8-5-10(13)9-3-6-11-7-4-9/h3-8H,1-2H3/b8-5+
Relevant articles related to 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one:
|
Article |
Source |
|
Structure-Based Discovery of Pyrimidine Aminobenzene Derivatives as Potent Oral Reversal Agents against P-gp- And BCRP-Mediated Multidrug Resistance |
Qiu, Qianqian,Zou, Feng,Li, Huilan,Shi, Wei,Zhou, Daoguang,Zhang, Ping,Li, Teng,Yin, Ziyu,Cai, Zilong,Jiang, Yuxuan,Huang, Wenlong,Qian, Hai , p. 6179 - 6197 (2021/06/01) |
|
Discovery of highly potent tubulin polymerization inhibitors: Design, synthesis, and structure-activity relationships of novel 2,7-diaryl-[1,2,4]triazolo[1,5-a]pyrimidines |
Huo, Xian-Sen,Jian, Xie-Er,Ou-Yang, Jie,Chen, Lin,Yang, Fang,Lv, Dong-Xin,You, Wen-Wei,Rao, Jin-Jun,Zhao, Pei-Liang , (2021/05/10) |
6.Buy 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one with the best price .
Hangzhou Mole's Science & Technology Co.,Ltd. is a quality supplier of 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one 55314-16-4.
